Clinical Studies

Our current clinical research is focused on metabolic bone disorders including fibrodysplasia ossificans progressiva (FOP). Our observational studies include patient registries and sample biobanking for rare bone diseases. In addition, our team is involved in multiple Phase 2 and Phase 3 interventional studies for metabolic bone diseases.

 

The Metabolic Bone Clinic

The UCSF Metabolic Bone Clinic in the Division of Endocrinology and Metabolism focuses in rare, genetic, or unusually complicated bone diseases. Our experts include Drs. Edward Hsiao, Dolores Shoback, and Steven Harris. We also work closely with other divisions at UCSF, including Medical Genetics, Orthopedics, Nephrology, and Medical Genetics.

For more information, and instructions for referrals to the clinic, please visit the UCSF Division of Endocrinology website: UCSF Metabolic Bone Clinic


 

Active Clinical Trials

For updated information about our ongoing clinical trials, please see the following links at clinicaltrials.gov:

  1. An Open-Label Extension Study of Palovarotene Treatment in Fibrodysplasia Ossificans Progressiva (FOP)
  2. Study to Assess the Efficacy and Safety of 2 Dosage Regimens of Oral IPN60130 for the Treatment of Fibrodysplasia Ossificans Progressiva (FOP).
  3. A Rollover Study to Further Evaluate the Safety and Efficacy of Palovarotene Capsules in Male and Female Participants Aged ≥ 14 Years With Fibrodysplasia Ossificans Progressiva (FOP) Who Have Completed the Relevant Parental Studies.
  4. An Efficacy and Safety Study of Palovarotene for the Treatment of Fibrodysplasia Ossificans Progressiva.


 

 

Email and our research contacts should not be used for clinical concerns. Call 911 if you have a clinical emergency or need immediate clinical attention. The UCSF Endocrine Clinic can be contacted at 415-353-2350 for non-emergent clinical concerns, referrals, and for appointments. For prescription refills, please have your pharmacy fax their request to the UCSF clinic at 415-353-2337. In addition, we prefer that established patients contact the clinic through the secure UCSF MyChart system. Thank you.